Monday, October 3, 2011

Artificial metalloenzymes for olefin metathesis based on the biotin-(strept)avidin technology

Artificial metalloenzymes for olefin metathesis based on the biotin-(strept)avidin technology:

Chem. Commun., 2011, Advance Article DOI: 10.1039/C1CC15004A, Communication
Cheikh Lo, Mark R. Ringenberg, David Gnandt, Yvonne Wilson, Thomas R. Ward
Incorporation of a biotinylated Hoveyda-Grubbs catalyst within (strept)avidin affords artificial metalloenzymes for the ring-closing metathesis of N-tosyl diallylamine in aqueous solution. Optimization of the performance can be achieved either by chemical or genetic means.

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