Observation of Fe(V)=O using variable-temperature mass spectrometry and its enzyme-like C–H and C=C oxidation reactions

Observation of Fe(V)=O using variable-temperature mass spectrometry and its enzyme-like C–H and C=C oxidation reactions:

Observation of Fe(V)=O using variable-temperature mass spectrometry and its enzyme-like C–H and C=C oxidation reactions

Nature Chemistry.
doi:10.1038/nchem.1132

Authors: Irene Prat, Jennifer S. Mathieson, Mireia Güell, Xavi Ribas, Josep M. Luis, Leroy Cronin & Miquel Costas

Variable-temperature mass spectrometry, isotopic labelling and computational analysis have been used to characterize a metastable non-haem oxo-iron(V) intermediate generated at cryogenic temperatures, as well as to study its cis-dihydroxylation reaction with olefins. The study provides experimental evidence for the existence of this powerful and biologically important oxidant, under conditions relevant to catalysis.

RA: Leroy Cronin group is a materials chemistry group pioneered with cryo-mass and VT-mass spectrometric techniques. They have also studied many reaction dynamics with MS and other instrumental methods (e.g. Science 2010 from this group).