Thursday, August 25, 2011

Iridium Diamine Catalyst for the Asymmetric Transfer Hydrogenation of Ketones

Iridium Diamine Catalyst for the Asymmetric Transfer Hydrogenation of Ketones: Thumbnail image of graphical abstract
A simple and very efficient chiral aqua iridium(III) diamine complex leads to excellent enantioselectivities in the asymmetric transfer hydrogenation of various α-cyano and α-nitro ketones. The catalyst provides the ortho-substituted aromatic alcohols with high ee values. The diamine ligands can be used directly as chiral ligands; conversion to the corresponding sulfamide is not necessary.

How do the get the N,N'-dimethylDPEN?

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