Tris(bispyrene-bipyridine)iron(II): A Supramolecular Bridge for the Biofunctionalization of Carbon Nanotubes via π-stacking and Pyrene/β-Cyclodextrin Host–Guest Interactions

Tris(bispyrene-bipyridine)iron(II): A Supramolecular Bridge for the Biofunctionalization of Carbon Nanotubes via π-stacking and Pyrene/β-Cyclodextrin Host–Guest Interactions: "

Bridging bio to nano: A simple procedure is reported to fabricate a biosensor by using the capacities of pyrene derivatives which are attached to nanotube sidewalls and to form host–guest complexes with β-cyclodextrins (see figure). A trisbipy iron(II) complex containing six pyrene groups was synthesized and attached to carbon nanotubes. β-Cyclodextrin modified glucose oxidase was used as model enzyme to form the pyrene/β-cyclodextrin inclusion complex, thus efficiently immobilizing the enzyme.

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