Tuesday, August 23, 2011

Targeted and multifunctional arene ruthenium chemotherapeutics

Targeted and multifunctional arene ruthenium chemotherapeutics:

Dalton Trans., 2011, Advance Article
DOI: 10.1039/C1DT11007A, Perspective
Gregory S. Smith, Bruno Therrien
This perspective review presents an overview of ruthenium complexes with biologically active molecules that produce bioorganometallic molecules of chemotherapeutic significance.

I (TR) dont think that the medical apps are very realistic (otherwise pharma would be more deeply into this area), but the chemistry is fascinating. This is the group that popularized [(C6Me6)Ru(H2O)3]++.

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